Understanding Vitamins for AMD

Age-Related Eye Disease Study (AREDS)

In 2001, Age-Related Eye Disease Study (AREDS) researchers reported that a vitamin supplement called the AREDS formulation could reduce the risk of developing advanced age-related macular degeneration (AMD).

In 2006, the same research group, based at National Institute of Health’s National Eye Institute, began a second study called AREDS2. They wanted to determine if they could improve the AREDS formulation. They tested the following: adding antioxidants lutein and zeaxanthin, and omega-3 fatty acids, removing beta-carotene, and lowering the dose of zinc.

AREDS 1

What is the original AREDS vitamin formulation?
-500 milligrams (mg) of vitamin C
-400 international units of vitamin E
-80 mg zinc as zinc oxide
-15 mg beta-carotene
-2 mg copper as cupric oxide

AREDS2

What modifications were tested in AREDS2 vitamins?
-10 mg lutein and 2 mg zeaxanthin
-1000 mg of omega-3 fatty acids (350 mg DHA and 650 mg EPA)
-25 mg zinc
No beta-carotene

Why did they change the AREDS2 formulation? Why add lutein/zeaxanthin and omega-3 fatty acids? Previous studies had found that dietary intake of lutein/zeaxanthin and omega-3 fatty acids is associated with a lower risk of developing advanced AMD.

Why eliminate beta-carotene? During the AREDS trial, two large trials funded by the National Cancer Institute found that beta-carotene may increase lung cancer risk among people who smoke. Lutein and zeaxanthin are in the same family of nutrients as beta-carotene and are believed to have important functions in the retina. Therefore, the researchers theorized that lutein/zeaxanthin might be a safer and possibly more effective alternative than beta-carotene.

Why reduce the vitamin zinc? Although zinc was found to be an essential component of the AREDS formulation in the original trial, some nutritional experts recommended a lower dose.

You can buy AREDS2 formula eye vitamins at all of The Optical Gallery locations at The Eye Associates.

Blindness – a Major Fear


<img alt= "blindness would inhibit bikers taking an early morning ride"

Blindness causing fear of losing the active lifestyle that you now enjoy.

Blindness – Third Biggest Fear

A Prevent Blindness America Survey found that blindness ranked third as a major fear. Number 1 and 2 were cancer and heart disease. Of course, there are ways to prevent vision loss. The best way is to have a yearly comprehensive dilated eye exam. Being proactive always has positive benefits on your health and your eye health.

Common Causes of Blindness

Cataracts are the leading cause of preventable blindness worldwide. Cataract surgery is a very common surgery in the United States, but in less developed countries, people often go blind. This is due to the inaccessibility of eyecare. But even here in the US, we find that since cataracts are slow growing and they usually affect the vision in such a gradual way. Often people are unaware they have them and don’t realize they have such poor vision.

Diabetic retinopathy is another common cause of blindness in people under age 65. Diabetes affects your entire body, including your eyes. According to The American Academy of Ophthalmology, diabetics are 25 times more likely to lose vision than those without this disease. Diabetic retinopathy is the most common complication of diabetes. The longer you have diabetes, the more likely it is that you’ll develop diabetic retinopathy.Many patients with this condition are asymptomatic at its most treatable stage, so diabetics are strongly advised to have routine yearly comprehensive dilated eye examinations.

Another cause of vision loss is glaucoma. Half of all people with glaucoma risk permanent damage because they are unaware that they have it. A comprehensive dilated eye exam is the only way to determine whether these problems are present so appropriate treatment can be initiated.

As you can see, serious and sight-threatening eye diseases do not always present symptoms, but they can be diagnosed during a eye exam. Often treatment can be given before damage occurs. Vision is your most valued of all senses, for everyday activities and even your safety. An eye exam should be part of your yearly schedule. It could save your sight!

Click here or call 1-866-865-2020 for a comprehensive eye exam with one of our Board Certified Physicians.